a tool for identifying drug-targetable redox-active disulphides

Cytochrome P450 2C5

Intramolecular

Cysteine 175 and cysteine 179

A redox-regulated disulphide may form within Cytochrome P450 2C5 between cysteines 175 and 179.

Details

Redox score ?

63

PDB code

Structure name

structure of mammalian cytochrome p450 2c5

Structure deposition date

2000-01-11

Thiol separation (Å)

5

Half-sphere exposure sum ?

82

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

175

Residue number B

179

Peptide name

Cytochrome P450 2C5

Ligandability

Cysteine 175 of Cytochrome P450 2C5

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 179 of Cytochrome P450 2C5

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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